For me, the Yanagisawa TWO1 hands-down outplays its direct competitor, the Yamaha YTS-62. Playing these horns side by side, the Yany has noticeably superior tone, response, and ergonomics while being in the same price-range as the YTS-62. I also play-tested this horn against a Custom Z, Eastman, P. Mauriat, and even a Selmer Reference 54, and it was the clear winner even over the higher priced horns.
Even with the additional import duties and fees, Thomann Music has by far the best online price available, especially if you live in North America, where Yanagisawa horns are severely marked up. It arrived to me in the U.S. just ten days after placing the order and was packaged extremely well. Apart from the action being a bit heavier than I would prefer, this horn plays great straight out of the box, and I imagine it will play even better once setup properly by a good tech.
For anyone looking for a solid pro-horn, especially as a North American resident, this is about the best value instrument available.